The (I feel) often hilarious head of the PhoneGap cross-platform framework at Adobe, Brian LeRoux, is coming to give a talk in Chicago Mon Jan 21 and I've got my ticket and am so pumped about it! I feel like he (and frankly the Adobe team that recently came to 1871 for "Create The Web") has a great grasp on where the web/internet/javascript is headed and urge you to attend.
After working for startups using rivals Titanium Appcelerator and Sencha Touch, I am definitely both feet planted in the PhoneGap camp. There are a great many bad PhoneGap apps out there and Facebook pulled theirs for a native solution. However, those apps may have spent just a day on ui/ux and user testing and trust the powers that be at Jquery or wherever to be concerned about mobile performance when *aha* user-experience matters to people. Companies are concerned over whether Internet Explorer 6 and Konqueror are supported. Your average customer is a iPhone user who only cares about webkit so put your resources into ui/ux at first and worry about the backend and scaling later.
See you there!