Genesis Therapeutics is building a world-class computational team to solve problems in drug discovery through machine learning, biophysical simulation, and computational chemistry. We are looking for an Infrastructure Engineer that is excited to help develop new medicines and play a critical role in building out our AI platform.
You Will
Work on our infrastructure team to maintain and grow our multi-cloud compute infrastructure that supports our ML model training, computational chemistry research, and ongoing drug discovery efforts
Build out our configuration and procedures for monitoring, resource allocation, and deployment automation, as we continue to grow our autoscaling compute clusters to handle larger workloads
Work on orchestration scheduling framework to increase our execution throughput, reliability, and compute utilization across heterogeneous pipelines
You Are
5+ years of experience building and maintaining cloud infrastructure at scale, e.g. within AWS or GCP
Proficient with Python, Bash, Terraform, Ray and Kubernetes
Ideally, experience building and maintaining compute clusters running distributed ML training jobs with 1,000+ GPUs
Nice to have: hands-on experience with physical hardware + datacenter management
What We Offer
The opportunity to work on high impact infrastructure that is used to accelerate the discovery of new medicines
A world-class, tight-knit team of good-hearted people across software, machine learning, computational chemistry, medicinal chemistry, and biology
Competitive salary and equity. Medical, dental, and vision insurance, and a 401(k) program
About Genesis Molecular AI
Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development. Our generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. Genesis is backed by premier AI and life science investors, including a16z, NVIDIA, Rock Springs Capital, Menlo Ventures, T. Rowe Price, Fidelity, and Radical Ventures. Genesis has also signed category-leading AI-pharma deals, the most recent of which was a significant expansion with Incyte (see coverage in Forbes and GEN) with a total potential deal value of several billion dollars.
Genesis is headquartered in San Mateo, CA, with a fully integrated laboratory in San Diego. We are proud to be an inclusive workplace and an Equal Opportunity Employer.
Skills Required
- 5+ years of experience building and maintaining cloud infrastructure
- Proficient with Python, Bash, Terraform, Ray, and Kubernetes
- Experience with compute clusters for distributed ML training jobs
What We Do
Genesis Molecular AI – headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego and offices in New York – is pioneering foundation models for molecular AI to unlock a new era of drug design and development. We are using a proprietary state-of-the-art generative and predictive AI platform called GEMS (Genesis Exploration of Molecular Space), to accelerate and optimize small molecule drug discovery. The GEMS platform integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction. GEMS accelerates hit ID through lead optimization and candidate selection by generating promising molecules for synthesis and experimental testing, and iterating this process through cycles of AI-enabled discovery and optimization. We have leveraged GEMS to build an internal pipeline with multiple programs against high-value targets, including data-poor and canonically undruggable targets where GEMS is uniquely advantaged. In addition, Genesis has signed AI platform collaborations across a range of therapeutic areas including Gilead (2024), and Incyte (2025). Genesis has raised over $300M in funding from top AI, technology and biotech investors, including Andreessen Horowitz, Rock Springs Capital, T. Rowe Price, Fidelity, Radical Ventures, NVentures (NVIDIA's VC arm), BlackRock, and Menlo Ventures. To learn more about Genesis Molecular AI, or current employment opportunities, please visit our website.
