Proposal Manager - Commercial

About Signant Health

At Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company that supports clinical trials with smart technology, scientific expertise, and hands-on operational support — so better data leads to better decisions in healthcare. We embrace AI and advanced technologies to enhance every aspect of what we do, from data analysis to operational efficiency.

Our teams work at the intersection of science, technology, and patient experience, delivering digital solutions powered by AI innovation that make clinical trials more efficient, more accurate, and more accessible around the world. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies across more than 90 countries and have contributed to hundreds of new drug approvals.

If you are motivated by meaningful work, global impact, and innovation in clinical research and digital health — including the opportunity to work with cutting-edge AI technologies — you will find purpose and opportunity at Signant Health.

About the Role

The Proposal Manager is the single point of accountability for a proposal from qualification through submission — the quarterback who drives the cross-functional process. This role translates a sales opportunity into an accurate, competitively priced, on-time proposal by pulling the right inputs from Science/Product and Operations, resolving conflicts and gaps, and making judgment calls when information is incomplete. The Proposal Manager owns the proposal timeline and the integrity of the numbers inside it, and acts as a trusted business partner to Sales rather than an order-taker.

The quality of our proposals, pricing competitiveness, and turnaround time directly affects win rate. This is a high-visibility role with exposure to executive leadership.

Key Accountabilities

• Own the end-to-end proposal process: serve as the central point of contact from the moment an opportunity is qualified through final proposal delivery, coordinating every workstream needed to produce it.
• Drive cross-functional input gathering: identify exactly which inputs are needed from Sales, Operations, and Delivery; request them proactively; and chase down open items until they are closed — nothing sits unresolved without a named owner and a date.
• Build and validate pricing and budget: assemble the budget/cost model, apply the correct pricing framework and rate cards, sanity-check assumptions against scope, and raise concerns early to ensure a high-quality customer deliverable.
• Maintain the proposal timeline: set milestones working backward from the customer deadline, track status against them, and escalate early when a dependency is at risk rather than after the deadline slips.
• Translate scope into an accurate proposal: convert sales and technical input into clear, well-structured proposal content, including value proposition, scope of work, assumptions, and pricing tables that hold up under scrutiny.
• Partner with Sales, not just support Sales: bring a business mindset to shape the deal — question scope that doesn't hold together, surface margin or delivery risk, and offer alternatives rather than passively formatting whatever is requested.
• Manage version control and approvals: route the proposal through the required internal review and approval chain and maintain a clean audit trail of changes and approvals.
• Run proposal debriefs: capture what worked and what didn't after submission or award/loss, and feed lessons learned back into templates, pricing tools, and process.
• Continuously improve the process: identify recurring bottlenecks and drive fixes in partnership with Commercial Operations leadership.

Knowledge, Skills & Attributes

Essential:

• Bachelor's degree in business, finance, life sciences, or a related field, or equivalent work-related experience.
• Minimum of five years of experience in proposal management, deal desk, sales operations, pricing, or a similarly cross-functional commercial role.
• Demonstrated ownership of budgets, pricing models, or financial deliverables with a low tolerance for error.
• Advanced Excel skills; comfortable working inside CRM/CPQ or quoting systems (e.g., Salesforce, Certinia, or similar).
• Ability to utilize company-issued and approved AI tools to support productivity, efficiency, and quality of work, while maintaining accountability for all AI-generated outputs.
• Life Sciences industry experience required; pharmaceutical or clinical trial industry experience strongly preferred.
• Demonstrated ability to work cross-functionally and communicate effectively with all levels of the organization, including senior and executive leadership.
• Strong written communication skills — able to turn technical and commercial input into clear, client-ready language.
• Strong analytical and critical thinking skills with the ability to identify areas for improvement and provide strategic, informed recommendations.
• Team-oriented with a proactive, positive attitude and strong collaborative working style; ability to manage multiple competing priorities in a fast-paced, dynamic environment.

Desirable:

• Experience in the pharmaceutical, clinical trial, or life sciences industry at a senior level.
• Experience with Salesforce, Certinia, or other CPQ/quote-to-cash tooling or comparable contract management software.
• Prior experience partnering directly with Sales in a quota-carrying environment.
• Experience contributing to or leading process improvement initiatives within contracts, proposals, or commercial operations.

Why Signant Health?

At Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission.

We offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo.

If you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it.

At Signant Health, accepting difference isn't enough — we celebrate it, we support it, and we nurture it for the benefit of our team members, our clients, and our community. We are proud to be an equal opportunity workplace and an affirmative action employer, committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status. Prior to their start date, all new hires are required to be verified through a thorough background check and identity verification to confirm eligibility for employment.

Unsolicited resumes submitted by agencies or third-party recruiters directly to hiring managers or any Signant Health employee will not be considered and will not obligate Signant Health to any fees or terms associated with the submission.

#LI-SR1