GenBio AI is building the Virtual Cell World Model - a persistent, multimodal AI system that predicts, simulates, and ultimately programs cellular behavior. Rather than producing isolated predictions, the Virtual Cell enables scientists to query cellular states, perform virtual perturbations, and design new biological interventions within a unified computational world. Together with AIDO Foundry, our AI-native engineering framework for automating Virtual Cell development, we are building the software infrastructure for the next generation of AI-driven drug discovery.
As our team scales, we are seeking a highly execution-oriented Director of Engineering to drive a culture of engineering excellence and rapid delivery at our Palo Alto office. The core objective of this role is to translate our long-term vision into actionable engineering roadmaps, enforce rigorous timelines, and successfully operationalize our research into production-grade systems.
Responsibilities
Translate high-level vision into concrete, actionable engineering roadmaps, driving a high-tempo shipping cadence and ensuring the team consistently hits critical product and infrastructure milestones on strict timelines.
Actively contribute to the codebase as a hands-on engineering leader, writing code, reviewing pull requests, and setting the technical bar while coordinating complex efforts across diverse product and infrastructure teams.
Build the critical operational bridge between research and engineering, architecting solutions to transition cutting-edge, experimental foundation models into robust, scalable, and highly available production systems.
Instill a relentless culture of rigor, velocity, and code quality by defining and enforcing uncompromising standards for automated testing, CI/CD pipelines, and optimal developer experience.
Actively manage, mentor, and level up both junior and senior engineers, providing hands-on coaching, performance feedback loops, and architectural guidance to maximize their growth and technical output.
Partner closely with the executive leadership team and AI research leads to proactively identify critical path dependencies, clear blockers, and align technical execution with the company’s ambitious scientific and commercial goals.
Qualifications
Extensive engineering experience (10+ years), with at least 5 years in senior leadership roles, demonstrating a proven track record of managing managers, scaling high-performing teams, and maintaining hands-on technical proficiency.
Exceptional technical expertise in modern AI infrastructure, with deep, hands-on experience building, scaling, and deploying complex generative AI products and massive foundation models into production environments.
Demonstrated execution-oriented mindset with the ability to swiftly transition complex, ambiguous technologies from a conceptual R&D phase into a highly reliable, commercial-grade enterprise platform.
Deep architectural understanding of high-performance computing, strategic GPU cluster optimization, and the unique distributed systems challenges involved in training and serving foundation models at scale.
Outstanding cross-functional orchestration skills, with the ability to manage complex project timelines and keep diverse, fast-moving teams focused on critical deliverables.
Preferred Qualifications
Domain knowledge or prior experience working within computational biology, genomics, drug discovery, or integrating AI into scientific software platforms.
Familiarity with building robust internal developer platforms, complex MLOps pipelines, or unified frameworks (similar to our AIDO Foundry) to accelerate AI deployment.
Prior experience at an early-stage, hyper-growth AI startup, demonstrating the ability to thrive in a highly ambiguous and fast-paced environment.
Skills Required
- 10+ years of engineering experience
- At least 5 years in senior engineering leadership roles
- Experience managing managers and scaling high-performing engineering teams
- Maintained hands-on technical proficiency, including coding and code review
- Deep hands-on experience building, scaling, and deploying generative AI products and foundation models in production
- Ability to transition ambiguous R&D technologies into reliable enterprise platforms
- Architectural expertise in high-performance computing, GPU cluster optimization, and distributed systems for foundation model training and serving
- Strong cross-functional orchestration and project timeline management skills
- Domain knowledge or experience in computational biology, genomics, drug discovery, or scientific software
- Experience building internal developer platforms, MLOps pipelines, or unified AI deployment frameworks
- Experience at an early-stage, hyper-growth AI startup
What We Do
GenBio.AI, Inc. (GenBio AI) is an innovative global startup dedicated to developing the world's first AI-driven Digital Organism, an integrated system of multiscale foundation models for predicting, simulating, and programming biology at all levels. Our goal is to achieve comprehensive, actionable empirical understandings of the mechanisms underlying all organismal physiologies and diseases. This will pave the way for a new paradigm in drug design, bio-engineering, personalized medicine, and fundamental biomedical research, all powered by Generative Biology. Our founding team consists of world-renowned scientists and researchers in AI and Biology from prestigious institutions such as CMU, MBZUAI, WIS, alongside prominent financial investors. GenBio AI, a true global effort from day one, is establishing offices in Palo Alto, Paris, and Abu Dhabi.
