Scientist, Neurobiology

Reposted 6 Days Ago
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Cambridge, MA
In-Office
100K-127K Annually
Expert/Leader
Biotech
The Role
The Scientist in Neurobiology will conduct experiments on neural cell types, analyze data from in vivo and in vitro studies, and maintain documentation.
Summary Generated by Built In

Company

Each day, the lives of more than 2 billion people across the globe are impacted by chronic diseases. Moreover, the economic burden on society of treating chronic disease is spinning out of control. Today, this dire situation appears unlikely to change as >95% of global healthcare costs are spent on treating rather than preventing chronic diseases. Etiome is a privately held early-stage company that is applying advanced biological and computational platforms to discover breakthroughs in detection of and intervention against the etiologies that drive progression from health to disease. Our goal is to leverage our proprietary platforms to disrupt the current approach of treating chronic disease after symptoms onset. We endeavor to provide true health care rather than sick care to individuals that are at risk of progressing to disease.

Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Position Summary:

Etiome is seeking a highly motivated and experienced scientist focusing on neurobiology. 

Responsibilities:

  • Planning, executing, and analyzing hands-on, wet-bench experiments involving primary and iPSC-derived neural cell types including but not limited to MEA studies, sc/snRNAseq studies, immunohistological studies, etc.  
  • Culturing and maintaining primary and iPSC-derived cell cultures, including co-cultures and organoids
  • Planning, executing, and analyzing in vivo studies focused on neurobiology
  • Analyzing and interpreting single cell/single nuclei RNAseq studies
  • Interpreting, organizing, and presenting biological data
  • Maintaining good documentation

Requirements:

  • Expertise in neuroscience and neurodegenerative disorders, preferably Alzheimer's Disease
  • Ph.D. in Neurobiology, biology, molecular biology, cellular biology or similar with 0-4 Years of experience post Ph.D.
  • Hands on experience with in vitro assays using iPSC-derived neurons and relevant co-cultures, microelectrode array technology, beta amyloid and/or tau seeding assays, etc.
  • Hands on experience with Alzheimer’s Disease relevant in vivo mouse models
  • Experience with bulk and single cell/single nuclei RNAseq data generation and data analysis workflows
  • Strong organization and time management skills
  • Strong oral and written communication skills
  • Attention to detail and good documentation practices

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. 

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.


The salary range for this role is $100,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Etiome, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Etiome, Inc.'s good faith estimate as of the date of publication and may be modified in the future.

Top Skills

Ipsc-Derived Neural Cell Types
Microelectrode Array Technology
Rnaseq Analysis
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The Company
HQ: Cambridge, MA
475 Employees
Year Founded: 2000

What We Do

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability.

Since its launch in 2000, the firm has applied a unique, hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $30 billion in aggregate value. To date, Flagship is backed by >$3 billion of aggregate capital commitments, of which over $1.5 billion has been deployed toward the founding and growth of its pioneering companies alongside >$10 billion of follow-on investments from other institutions.

The current Flagship ecosystem includes Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO), Moderna Therapeutics (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).

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