GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.
Raleigh-Durham, NC

Senior Software Program Manager #1956

| Raleigh-Durham, NC +2 more
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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit

Grail is building the software to run population-scale clinical studies and future products using state of the art technologies and software engineering. We are looking for a Senior Software Program Manager to be responsible for ensuring the successful deployment of projects under development in the clinical and software engineering teams. This will include process development, establishment and management of timelines, tracking completion of software life cycle deliverables, facilitation of interdepartmental communication, meeting management, creation of slide sets and other communication tools. 

A successful candidate will have a thorough understanding of process and system development. Hands on Project Management of multi-projects. Proven creative ability to move technology projects forward while addressing and overcoming challenges. It is important that this person have the ability to work across functions and incorporate broad viewpoints into the deliverables.

You Will:

  • Hands on Project Management of multi-projects. Document and deliver assigned projects on-time from inception through completion.
  • Develop and maintain product development plans including key milestones and entry or exit criteria.
  • Ensure you and the project team stay focused on critical tasks, tactfully pushing back on work outside of scope. 
  • Identify and manage project risks.
  • Apply sound project management methodologies.
  • Prepare and disseminate project status reports.
  • Work cross-functionally to create shared solutions.
  • Generate creative solutions to project processes and quality related challenges.
  • Examine functional issues from a broader organizational perspective and provide solutions to issues and gaps.
  • Participate in and/or drive departmental or interdepartmental projects.
  • Schedule and conduct project meetings as required.
  • Develop project metrics.

Your Background Should Include:

  • 7+ years of experience managing large scale software projects.
  • Bachelor’s degree in computer science, engineering or life science related field or equivalent experience; advanced degree preferred.
  • Experience across the software development life cycle using methodologies such as Agile, Scrum or similar.
  • Experience developing clinical systems or production systems in the life science space, e.g. electronic data capture system, eTMF, IXRS or CTMS is a plus.
  • Demonstrated ability to think strategically across the organization.
  • Proficiency with office automation and project management tools.
  • Proven interpersonal communication (written and verbal), and organizational skills.
  • Ability to motivate a team to work in a fast-paced and changing environment.
  • A sound work ethic and demonstrated ability to deliver assignments on time. 
  • Knowledge of FDA Regulations, in particular, 21 CFR Part 11 and the Software Development Guidance documents is a plus.

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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Technology we use

  • Engineering
  • Sales & Marketing
    • C++Languages
    • GolangLanguages
    • JavascriptLanguages
    • PythonLanguages
    • RLanguages
    • SqlLanguages
    • ReactLibraries
    • AWSLibraries
    • S3Libraries
    • EC2Libraries
    • GitLibraries
    • KubernetesFrameworks
    • DockerFrameworks
    • ProtobufFrameworks
    • BazelFrameworks
    • PhabricatorFrameworks
    • MongoDBDatabases
    • MySQLDatabases
    • RedisDatabases
    • SQLiteDatabases
    • SalesforceCRM

What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Friends outside of work
Eat lunch together
Intracompany committees
Daily sync
Open door policy
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Open office floor plan
Dedicated Diversity/Inclusion Staff
Unconscious bias training
Diversity manifesto
Mean gender pay gap below 10%
Diversity Employee Resource Groups
Hiring Practices that Promote Diversity
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability Insurance
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Wellness Programs
Onsite Gym
Team workouts
Retirement & Stock Options Benefits
Company Equity
Performance Bonus
Child Care & Parental Leave Benefits
Child Care Benefits
Generous Parental Leave
Flexible Work Schedule
Remote Work Program
Family Medical Leave
Company sponsored family events
Vacation & Time Off Benefits
Unlimited Vacation Policy
Paid Holidays
Paid Sick Days
Perks & Discounts
Casual Dress
Commuter Benefits
Free Daily Meals
Game Room
Happy Hours
Professional Development Benefits
Job Training & Conferences
Diversity Program
Cross functional training encouraged
Promote from within
Mentorship program
Online course subscriptions available

An Insider's view of GRAIL

How does your team reward individual success?

People grow their skills both by learning how to rapidly build scalable software systems, but also by partnering with scientists and other domain experts to better understand, model, and envision the systems we will need. We enable and empower our engineers to lead this process and grow with our systems as they make the future of GRAIL a reality.

Tristan Matthews

Senior Director, Software Engineering

What projects are you most excited about?

GRAIL has a unique opportunity to scale our operations to add value with our early detection test. Our automation team works on the full spectrum of projects from low-level instrument investigations to overall architectures of processing facilities. I'm excited by projects that push the boundaries of lab automation, and that's what GRAIL is doing.

David Jenions

Principal Automation Engineer

What does career growth look like on your team?

Our mission, to detect cancer early, is truly seeking a needle in many haystacks. Our lab has a very complex and sophisticated assay to execute. We leverage cross-training and mentorship programs where new teammates learn the ropes from senior staff. My team sets people up for success by turning tasks into learning opportunities.

Maryam Hosseini

Director, Laboratory Operations

How do your team's ideas influence the company's direction?

The biological problem we're trying to solve is a complex machine learning problem with human lives at stake. From a software engineering point of view, taking massive data, organizing it, building tools to mine it, and deliver results in a scalable, secure, and clinically compliant manner are areas of innovation. This, for me, is my dream job!

Satnam Alag

SVP, Software Engineering

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