Advisor-Receptor Pharmacologist

| Indianapolis, IN
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At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Do you have significant hands-on experience working with G-protein coupled receptors (GPCRs) and a strong grasp of the biology and pharmacology of GPCRs? Our Molecular Pharmacology team is an innovation-focused organization using groundbreaking technologies to deliver maximum benefit to our patients. We are looking for a research scientist with a background in G-protein coupled receptors (GPCRs) who can work collaboratively to help us discover small molecule therapeutics for disease targets. You will join an innovative research group where you will learn industrial drug discovery by working with experts in pharmacology, biophysics, bioanalytical, chemical biology, medicinal chemistry, structural biology, and disease biology to discover and optimize molecules for human testing.

Responsibilities:

Top candidates for this position will be expected to:

  • Drive in vitro pharmacology approaches for drug discovery projects in diverse therapeutic areas (diabetes, obesity, pain, neurodegeneration, immunology).
  • Apply knowledge of GPCRs to enable drug discovery using cellular and/or biochemical approaches.
  • Develop cell-based and biochemical assays for potency, selectivity, and mechanism of action to enable small molecule drug discovery for GPCRs.
  • Apply pharmacologic models to analyze and interpret data
  • Have broad experience with multiple different techniques and approaches (e.g. cell assays, radioactive binding, receptor biochemistry, and/or other molecular and proteomic approaches).
  • Tackle and solve difficult scientific problems through mechanistic experimentation.
  • Learn and practice the science of drug discovery.
  • Contribute to scientific projects where solutions are developed through teamwork.
  • Demonstrate high learning agility regarding grasping and exploiting new scientific concepts and methods across multiple subject areas.
  • Partner with cross-functional partners to drive high-speed innovation.
  • Embrace diversity of thought, background and experience to deliver creative solutions.
  • Possess strong communication (oral, written), organizational, and leadership skills.

Qualifications:

  • Ph.D. in cell biology, pharmacology, chemical biology, biochemistry or closely related field.
  • Demonstrated track record for publication and presentation of research results.



Additional Skills/Preferences:

  • Demonstrated technical and intellectual proficiency in the conduct of high-quality research to answer mechanistic biology problems.
  • Postdoctoral training.
  • Experience in the fields of immunology, diabetes, or neuroscience.
  • Knowledge of other classes of receptor targets.
  • Experience with a wide variety of standard lab techniques e.g. CRISPR, biochemical assays, proteomics, chemical biology, molecular biology.
  • Good interpersonal and collaboration skills.
  • Demonstrated initiative and appropriate risk-taking.
  • Strong technical skills to supply business value.
  • Ability to prioritize and manage multiple activities.



Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( [email protected] ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

More Information on Eli Lilly and Company
Eli Lilly and Company operates in the Biotech industry. The company is located in Indianapolis, IN and Indianapolis, IN. Eli Lilly and Company was founded in 1876. It has 39451 total employees. It offers perks and benefits such as Flexible Spending Account (FSA), Disability insurance, Dental insurance, Vision insurance, Health insurance and Life insurance. To see all 55 open jobs at Eli Lilly and Company, click here.
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