GRAIL

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured.

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Research Associate II/Sr Research Associate - Assay Development - Early Cancer Detection - #1592

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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com.

Are you a research associate with experience in molecular assay development? This could be the role for you! GRAIL is seeking a Senior Research Associate on the Assay Development team at our headquarters in Menlo Park to perform studies to support the development and integration of GRAIL’s groundbreaking cancer screening products. The ideal candidate is a diligent positive team player with experience in product development of molecular assays.

You will:

Contribute to wet-lab assay development studies in support of IVD product development goals, including the planning and execution of experiments and preliminary data analysis under the guidance of senior scientists
Implement development and system integration studies to generate high quality data by following best practices of assay and instrument operations
Test and optimize custom protocols
Support technical troubleshooting investigations in support of implementation and operations teams
Document experimental details in electronic formats, and support documentation of study protocols and results
Support presentation of experimental results to cross-functional technical teamsEnsure laboratory activities are performed in compliance with safety guidelines
Ensure technical activities are in line with regulatory requirements (CAP/CLIA/FDA)

Your background includes:

B.S. or M.S. degree in Molecular Biology, Biochemistry, or similar field with a minimum of 3 years of work experience in an industry setting
Hands-on experience with Illumina NGS workflows including DNA extraction, library preparation highly preferred
Experience with standard nucleic acid analytical techniques (e.g, Fragment Analyzer, qPCR, Nanodrop)

Preferred skills...

Experience with the development and implementation of clinical laboratory tests under CAP/CLIA or FDA/regulated environments
Experience with the development, optimization, and troubleshooting of NGS assay protocols a plus
Experience with automated laboratory instrumentation such as liquid handlers and multi-functional work cells a plusExperience with statistical programming or software (e.g, R, JMP) a plus
Experience with design control and change control.

GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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Joerg Bredno

Principal Scientist, Computational Biology and Interpretation

WIDEN YOUR SCOPE

A huge data set with an even bigger impact

“Cancer is a nasty, diverse disease that can affect widely different regions in the genome,” Principal Scientist Joerg Bredno said, and understanding how and why cells change isn’t easy. Luckily, his team works with more than 12 petabytes of molecular data — which translates to more than 1 million gigabytes — and a high-performance scientific computing environment that can handle analysis at that scale. With these tools, Bredno’s team is building an even larger training data set for the next generation of GRAIL’s early detection, multi-cancer screening test, slated to roll out this year.

It is rewarding that we can see, learn and share relevant insights from our data that so far doesn't exist anywhere else in the world in this form.

Ting Ma

Associate Director, Data Engineering

ACCELERATE TOGETHER

A team united by passion, fueled by collaboration

GRAIL’s team sets lofty goals for its products, which require the unique talents and perspectives of every employee. Take one eight-month study that Associate Director Ting Ma worked on, parsing data from a GRAIL-sponsored clinical trial. Due to the volume of data, teamwork was imperative to define and implement clinical features, refine codes with robust test cases and tweak them as continuous feedback rolled in. The work is important, but that's not the only plus: “Cross-functional team collaboration is fun,” Ma said. “You get to learn so much while contributing to each project.”

GRAIL is taking on a challenge that is unprecedented. It can only become successful when people with different expertise collaborate deeply.

Ying Luan

Associate Biostatistical Director

UNCOVER NEW OPPORTUNITIES

Sharp talent, perpetually looking to learn more

There’s a reason top talent, like Associate Biostatistical Director Ying Luan, joins GRAIL. “Here, I knew I could have the opportunity to contribute to the development of innovative analysis methodologies,” Luan said. She’s now working on a diagnostic aid project, planning and designing validation for clinical studies. It’s a new area for her, but there’s plenty of support for learning new skills at the company: With resources like LinkedIn Learning, workshops and conferences, she finds footing in the field, while diversity and inclusion trainings connect her fully to GRAIL’s culture.

Post-launch activities and payer’s reimbursement were new to me when I joined GRAIL. But now, I’m learning new things on a daily basis with different stakeholders in mind.

What are GRAIL Perks + Benefits

GRAIL Benefits Overview

We’re committed to creating the best experience for everyone at GRAIL, ensuring that each member of our team has comprehensive benefits and resources to thrive at all stages of life, both at work and at home.

Culture

Volunteer in local community

Partners with nonprofits

Intermountain Healthcare

Open door policy

OKR operational model

Team based strategic planning

Open office floor plan

Employee resource groups

Employee-led culture committees

Hybrid work model

In-person all-hands meetings