Invitae makes it easy to access your genetic information, so you can take control of your health.
Colorado, CO

Senior/Principal Scientist - Oncology R&D Assay Development at Invitae

| Colorado, CO
Sorry, this job was removed at 11:14 a.m. (CST) on Wednesday, February 16, 2022
Find out who's hiring remotely in Colorado, CO.
See all Remote Data + Analytics jobs in Colorado, CO
Apply Now
By clicking continue you agree to Built In’s Privacy Policy and Terms of Use.


Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry by making genetic testing affordable and accessible for everyone to guide health decisions across all stages of life.


Residing in our Boulder, CO office, the Senior/Principal Scientist will join our Oncology R&D team and contribute key capabilities, expertise, and vision to our Personal Cancer Monitoring (PCM) oncology program. 

The Senior/Principal Scientist will be responsible for the design, execution, and critical evaluation of experiments and studies conducted in support of PCM product development, optimization, and scale-up efforts. This role will require multi-functional leadership skills and close collaboration with other scientists, engineers and technicians in the R&D, Software, Engineering, Quality Control, and Manufacturing departments to support evidence-based decision making and strategic process improvement. 

As a member of the PCM team, the Senior/Principal Scientist will play a key role in delivering outstanding systems, protocols, and processes—enabling high throughput NGS panel manufacturing and personal diagnostic testing, paving the way for the personalized healthcare revolution.


Job performance will involve a variety of activities including, but not limited to:

  • Designing and conducting wet lab and/or in silico experiments
  • Analysis of various large data sets, particularly NGS/WES results and reference genetics data
  • Interpreting scientific results and providing conclusions and recommendations
  • Communicating findings and educating audiences with diverse technical backgrounds
  • Generating ideas to improve existing technology and generate new technologies
  • Assist in algorithm development to produce new bioinformatic tools and pipelines
  • Recommend and guide process improvements to optimize PCM manufacturing for speed, quality, sustainability, and scalability.
  • Provide end-user support to PCM manufacturing operators, logistics specialists, and quality assurance personnel.
  • Lead by example to create an inclusive culture that values high engagement
  • Build and maintain positive and collaborative relationships cross-functionally to develop and improve technology and information transfer 
  • Working with collaborators both in industry and academia to create custom assay solutions
  • Creation of publication quality scientific communications 
  • Review, understanding, and compliance with ArcherDX HIPAA Security policies and procedures
  • Safeguarding the privacy and security of protected health information and European Union personal data
  • Processing and handling of European Union personal data only as directed by ArcherDX for purposes of personalized molecular pathology


  • 5+ years of laboratory experience (required) with 2+ years in industry (highly preferred)
  • Proficient with molecular genetics wet-lab techniques, particularly PCR and NGS library preparation (required)
  • Experience with NGS and bioinformatic tools for NGS analysis (required)
  • Familiar with scripting languages for executing and creating bioinformatic analysis such as Python, R, Bash, etc. (required), AWS, SQL (preferred)
  • Familiar with cancer genetics (required)


  • PhD in a life sciences discipline with demonstrated expertise in genetics/genomics.


  • Passion for enhancing healthcare outcomes with novel technology
  • Problem solver comfortable operating in the grey-space and driving forward with risk balanced decision making
  • Recognizes issues, problems, or opportunities and determines whether action is needed.
  • Demonstrates responsiveness and sense of urgency when pursuing goals and completing tasks
  • Ability to participate with others as a member of the team to ensure that demanding and difficult projects are handled smoothly and cooperatively to enhance the success of the projects and maintain strong relationships within all parts of the company.
  • Must exemplify Invitae/Archer’s values: Accountability, Care, Trust, Grit & Urgency
  • History of thriving in a fast-paced, dynamic environment
  • Inspirational people leader with a history of managing teams to deliver their best work
  • Able to organize, prioritize, and delegate tasks to efficiently move projects forward

This job description is not designed to cover nor contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

In Colorado, our competitive compensation package includes a base salary starting from $119,325.00. In determining the final salary offered, we will evaluate a specific candidate's geographic location, education, skills, and experience.

Invitae offers a competitive total rewards package, which includes healthcare coverage, 401k, and a broad range of other benefits, outlined below:

  • Health, dental, vision, short- and long-term disability, and basic life insurance coverage
  • Paid time off, holiday pay, parental leave, and other health and wellness supports

At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance.

See More
Apply Now
By clicking continue you agree to Built In’s Privacy Policy and Terms of Use.

Technology we use

  • Engineering
    • C#Languages
    • C++Languages
    • JavaLanguages
    • JavascriptLanguages
    • PHPLanguages
    • PythonLanguages
    • SqlLanguages

What are Invitae Perks + Benefits

Invitae Benefits Overview

At Invitae, our employees are the key to our continued success. Our culture is one of our most important strengths. A set of commitments we make to each other and to our customers to build a world-class organization in service of our mission. That is why Invitae proudly offers comprehensive perks and benefits program with choice and flexibility in mind.

Friends outside of work
Eat lunch together
Intracompany committees
Daily sync
Team owned deliverables
Team based strategic planning
Group brainstorming sessions
Open office floor plan
Dedicated Diversity/Inclusion Staff
Unconscious bias training
Diversity manifesto
Mean gender pay gap below 10%
Diversity Employee Resource Groups
Hiring Practices that Promote Diversity
Health Insurance & Wellness Benefits
Flexible Spending Account (FSA)
Disability Insurance
Dental Benefits
Vision Benefits
Health Insurance Benefits
Life Insurance
Pet Insurance
Wellness Programs
Team workouts
Mental Health Benefits
Retirement & Stock Options Benefits
Company Equity
Employee Stock Purchase Plan
Performance Bonus
Child Care & Parental Leave Benefits
Generous Parental Leave
Flexible Work Schedule
Remote Work Program
Family Medical Leave
Adoption Assistance
Return-to-work program post parental leave
Vacation & Time Off Benefits
Unlimited Vacation Policy
Paid Holidays
Paid Sick Days
Perks & Discounts
Beer on Tap
Casual Dress
Commuter Benefits
Company Outings
Free Daily Meals
Game Room
Stocked Kitchen
Some Meals Provided
Happy Hours
Pet Friendly
Recreational Clubs
Home Office Stipend for Remote Employees
Professional Development Benefits
Job Training & Conferences
Diversity Program
Lunch and learns
Cross functional training encouraged
Promote from within
Mentorship program

More Jobs at Invitae